Hepatoprotective effects of litchi (Litchi chinensis) procyanidin A2 on carbon tetrachloride-induced liver injury in ICR mice

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Hepatoprotective effects of litchi (Litchi chinensis) procyanidin A2 on carbon tetrachloride-induced liver injury in ICR mice

Drug tolerance, lacking liver regenerative activity and inconclusive inhibition of steatosis and cirrhosis by silymarin treatment during chronic liver injury have increased the demand for novel alternative or synergistic treatments for liver damage. Litchi fruit is abundant in polyphenolic compounds and is used in traditional Chinese medicine for treatments that include the strengthening of hep...

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Hepatoprotective effects of licochalcone B on carbon tetrachloride-induced liver toxicity in mice

Objective(s): The objective of this study was to investigate the hepatoprotective effect of licochalcone B (LCB) in a mice model of carbon tetrachloride (CCl4)-induced liver toxicity. Materials and Methods: Hepatotoxicity was induced in mice by a single subcutaneous injection (SC) of CCl4. The LCB was administered orally once a day for seven days (PO) as pretreatment at three doses of 1, 5, and...

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hepatoprotective effects of licochalcone b on carbon tetrachloride-induced liver toxicity in mice

objective(s): the objective of this study was to investigate the hepatoprotective effect of licochalcone b (lcb) in a mice model of carbon tetrachloride (ccl4)-induced liver toxicity. materials and methods: hepatotoxicity was induced in mice by a single subcutaneous injection (sc) of ccl4. the lcb was administered orally once a day for seven days (po) as pretreatment at three doses of 1, 5, and...

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Hepatoprotective and antioxidant effects of caesalpinia bonducella on carbon tetrachloride-induced liver injury in rats

The present study was carried out to evaluate the hepatoprotective and antioxidant effect of the methanol extract of Caesalpinia bonducella (MECB) (Family: Caesalpiniaceae) in Wistar albino rats. The different groups of animals were administered with carbon tetrachloride (CCl4) (30 % CCl4, 1 ml/kg b. wt. in liquid paraffin 3 doses (i.p.) at 72 h interval). The MECA at the doses of 50, 100 and 2...

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Hepatoprotective effects of licochalcone B on carbon tetrachloride-induced liver toxicity in mice

OBJECTIVES The objective of this study was to investigate the hepatoprotective effect of licochalcone B (LCB) in a mice model of carbon tetrachloride (CCl4)-induced liver toxicity. MATERIALS AND METHODS Hepatotoxicity was induced in mice by a single subcutaneous injection (SC) of CCl4. The LCB was administered orally once a day for seven days (PO) as pretreatment at three doses of 1, 5, and 2...

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ژورنال

عنوان ژورنال: Experimental and Therapeutic Medicine

سال: 2017

ISSN: 1792-0981,1792-1015

DOI: 10.3892/etm.2017.4358